Editorial Policy & Evidence Standards (E-E-A-T)

Published by the OncoGuides Clinical Governance Board

1. Commitment to Evidence-Based Onco-Fertility

OncoFertilityGuides produces content grounded strictly in peer-reviewed reproductive endocrinology, gynecologic oncology, randomized controlled trials, and consensus practice guidelines. Our clinical algorithms reflect authoritative guidance from:

American Society of Clinical Oncology (ASCO) — Fertility Preservation in Patients with Cancer Guidelines
European Society for Medical Oncology (ESMO) — Fertility Preservation and Post-Treatment Pregnancy in Cancer
American Society for Reproductive Medicine (ASRM) — Ovarian Tissue Cryopreservation Consensus
International Breast Cancer Study Group (IBCSG) — The POSITIVE Trial Protocol (NEJM 2023)

2. Clinical Evidence Hierarchy

We classify all recommendations using standard international evidence hierarchies:

Level A: Supported by multiple randomized controlled trials or prospective registration cohorts (e.g., POSITIVE trial, POEMS trial, PROMISE-GIM6, Green et al. CED equation).
Level B: Supported by multicenter clinical registries (e.g., ASRM Ovarian Tissue Cryopreservation Registry, FertiPROTEKT cohort).
Level C: Supported by expert consensus and physiological gonadal protection principles.

3. Commercial Independence & Non-Bias

OncoFertilityGuides maintains strict editorial independence. We do not accept pharmaceutical sponsorship, fertility clinic referral commissions, or paid product placements.